产品货号：
Z10930
中文名称：
Aminoacylase 1/ACY1抗体
英文名称：
Anti-Aminoacylase 1/ACY1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Aminoacylase 1/ACY1 Antibody |
| 指标别名 | ACY 1;ACY1;ACY1D;ACYLASE;Aminoacylase 1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,FCM,ELISA |
| 基因名称 | ACY1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human ACY-1/ACY1 recombinant protein (Position:E8-A354). |
| 成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Aminoacylase-1 is an enzyme that in humans is encoded by the ACY1 gene.This gene encodes a cytosolic,homodimeric,zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino acids to L-amino acids and an acyl group,and has been postulated to function in the catabolism and salvage of acylated amino acids.This gene is located on chromosome 3p21.1,a region reduced to homozygosity in small-cell lung cancer (SCLC),and its expression has been reported to be reduced or undetectable in SCLC cell lines and tumors.The amino acid sequence of human aminoacylase-1 is highly homologous to the porcine counterpart,and this enzyme is the first member of a new family of zinc-binding enzymes.Mutations in this gene cause aminoacylase-1 deficiency,a metabolic disorder characterized by central nervous system defects and increased urinary excretion of N-acetylated amino acids.Alternative splicing of this gene results in multiple transcript variants.Read-through transcription also exists between this gene and the upstream ABHD14A (abhydrolase domain containing 14A) gene,as represented in GeneID:100526760.A related pseudogene has been identified on chromosome 18. |
| Uniprot ID | Q03154 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot. |
| 基因名全称 | aminoacylase 1 |
| 蛋白名全称 | Aminoacylase-1 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Flow cytometry (FCM) 1～3μg/1×106 cells ELISA 1:100～1000 |
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